Dogs need a little more love during mosquito season

(ARA) - As a parent, you would never consider sending your child to school without the proper vaccinations. But did you know that according to the American Animal Hospital Association, about 50 percent of dogs in the United States go without preventative treatment for one of the most common diseases among canines?

Many people consider their dogs to be part of the family. And with mosquito season in full swing, dog owners should consider the best way to protect dogs against heartworm disease. Mosquito bites may be just a simple nuisance to humans, but they can spread heartworm disease without pet owners knowing, and dogs are most at risk of becoming seriously ill from the disease.

Heartworm used to be relatively contained in the American southeast, where warm, humid temperatures create good breeding grounds for mosquitoes. However, longer warm seasons in northern states and increased pet travel throughout the country have led to dramatic growth in the spread of heartworm over the past decade. Veterinarians in regions that were once considered low-risk now report heartworm outbreaks in their clinics, and the parasite can now be found in all 50 states.

Recognizing heartworm infection can be tricky. Symptoms include chronic cough and fatigue, but often the disease does not show any signs until it reaches an advanced stage. Eventually, heartworm can lead to lung, heart, liver and kidney failure.

Fortunately, heartworm prevention is simple, cost effective, and the best way to save dogs from the long, difficult and expensive treatment required once infection takes hold. Here are a few ways to keep dogs safe:

* The American Heartworm Society recommends getting your dog tested annually for heartworm. During these visits, talk to your veterinarian about the best method of prevention against the disease.

* Protect your dog with a monthly application of a heartworm preventative medication. Some topicals, like Advantage Multi for Dogs (imidacloprid + moxidectin) Topical Solution, also kill fleas and treat intestinal parasites, such as hookworms, roundworms and whipworms.

* During warmer months, keep your dog inside as much as possible during early morning and dusk when mosquitoes are most active.

Through annual testing and use of monthly preventatives, you can protect your dog from heartworm disease and help keep your dog healthy. If you haven't thought about prevention before, now is the time in the peak of mosquito season. For more information on heartworm prevention, visit advantagemulti.petparents.com.

Courtesy of ARAcontent


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FDA Announces Limited Return of Heartworm Drug to U.S. Market

The U.S. Food and Drug Administration (FDA) today announced a limited return of a reformulated heartworm prevention drug for dogs, which had been withdrawn because of serious, life-threatening adverse reactions, including loss of appetite, lethargy; vomiting, seizures, difficulty walking, jaundice (a yellowish appearance); and bleeding disorders, allergies, convulsions, followed in some cases by death.

ProHeart 6 (moxidectin) Sustained Release Injectable for Dogs, NADA 141-189, manufactured by Fort Dodge Animal Health, Overland Park, Kan., is an approved injectable sustained-release heartworm prevention product for dogs. FDA is concurring with its limited return to the U.S. veterinary market under a risk minimization and restricted distribution program designed to manage the re-introduction of ProHeart 6 to provide for safe, appropriate use of the product while minimizing risk to dogs.

"This is the first veterinary drug to be marketed under a risk minimization and restricted distribution program. Numerous drugs for use in people have been successfully marketed under similar programs," said Bernadette Dunham, D.V.M., Ph.D., director, FDA’s Center for Veterinary Medicine. "While we concur with the limited return of ProHeart 6 to the U.S. market, we strongly encourage veterinarians and pet owners to report any possible adverse reactions."

Heartworm disease is a serious and potentially fatal condition for dogs. The parasite that causes heartworm disease is transmitted through the bite of a mosquito.

The risk minimization and restricted distribution program is intended to educate veterinarians and pet owners regarding the possible risks associated with the use of ProHeart 6. Therefore, Fort Dodge Animal Health is requiring veterinarians who wish to purchase ProHeart 6 to register with the company and participate in a Web-based training program prior to obtaining the product.

The return of ProHeart 6 to the market is based on results of additional toxicological and pharmacologic studies by Fort Dodge Animal Health coupled with the low adverse reaction frequency in international markets.

In 2004, Fort Dodge Animal Health agreed to voluntarily recall the product from the market based upon FDA's concerns regarding reports of serious adverse reactions in dogs following the use of ProHeart 6. In response to FDA's concerns, the manufacturer conducted additional testing of its product, which indicated that residues of the solvents used in the manufacture of ProHeart 6 may cause allergic reactions.

The manufacturer has improved the manufacturing specifications for ProHeart 6 to decrease the presence of those residues and has marketed the product in international markets. Few adverse events have been reported with this reformulated product.

The ProHeart 6 label and Client Information Sheet have been revised to include updated safety information. The new label includes warnings not to administer the drug within one month of vaccinations, and to use the product with caution in dogs with pre-existing allergic diseases including food allergies, allergic hypersensitivity, and flea allergy dermatitis. The label also warns against administering the drug to dogs who are sick, debilitated, underweight, or who have a history of weight loss. In addition, the label’s Post-Approval Experience section has been updated to include information about adverse reactions based on voluntary post-approval drug experience reporting.

Dog owners who suspect their dog is experiencing an adverse reaction to ProHeart 6 should immediately contact their veterinarian to initiate appropriate veterinary care. Veterinarians should contact Fort Dodge Animal Health to report any adverse events at (800) 533-8536.